![]() ![]() Management of PMD includes the use of contact lenses, spectacles and a wide range of surgical techniques with variable results. PMD patients are at risk of corneal perforation after minimal ocular trauma or even spontaneously. It mainly affects the inferior cornea and induces against the rule irregular corneal astigmatism. Results: PMD is a rare ectatic disorder of the cornea that may resemble keratoconus especially at the early stages. Materials and Methods: Literature review via PubMed, Mendeley, Scopus and Google Scholar. ![]() Purpose: To describe the clinical features of Pellucid Marginal Degeneration (PMD) and to give an overview of current treatment options. This review describes the clinical features of PMD, its differential diagnosis and various management strategies presently available. Since patients with PMD make poor candidates for laser vision correction, an awareness of the topographical and slit-lamp features of PMD will be useful to clinicians screening for signs of corneal abnormality before corneal refractive surgery. Several surgical procedures have been used in an attempt to improve visual acuity when spectacles and contact lenses do not provide adequate vision correction. The vast majority of PMD patients are managed using spectacles and contact lenses. In rare cases, patients may present with a sudden loss of vision and excruciating ocular pain due to corneal hydrops or spontaneous perforation. Visual signs and symptoms include longstanding reduced visual acuity or increasing against-the-rule irregular astigmatism leading to a slow reduction in visual acuity. Unless corneal topography is evaluated, early forms of PMD may often be undetected however, in the later stages PMD can often be misdiagnosed as keratoconus. Ocular signs and symptoms of patients with PMD differ depending on the severity of the condition. The prevalence and aetiology of this disorder remain unknown. The condition is most commonly found in males and usually appears between the 2nd and 5th decades of life affecting all ethnicities. ![]() The differential diagnosis of peripheral corneal thinning and the challenge of the surgical management of pellucid marginal degeneration are briefly discussed.Pellucid marginal corneal degeneration (PMD) is a rare ectatic disorder which typically affects the inferior peripheral cornea in a crescentic fashion. We report a case of a 55‐year‐old woman with systemic scleroderma who presented with rapidly progressing against‐the‐rule astigmatism. Pellucid marginal degeneration is characterised by noninflammatory and progressive peripheral corneal thinning inferiorly, often with high against‐the‐rule astigmatism. No association has been reported between scleroderma and pellucid marginal degeneration, which is a rare bilateral corneal ectasia. Ocular involvement includes keratoconjunctivitis sicca, progressive shallowing of conjunctival fornices, peripheral ulcerative keratitis and eyelid tightness. Systemic scleroderma is a progressive multi‐system connective tissue disease. Pellucid marginal degeneration and scleroderma Pellucid marginal degeneration and scleroderma ![]()
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